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Books by Sean Ekins






Collaborative Computational Technologies for Biomedical Research(1st Edition)
by Sean Ekins, Alpheus Bingham, Antony J. Williams
Hardcover, 576 Pages, Published 2011 by Wiley
ISBN-13: 978-0-470-63803-3, ISBN: 0-470-63803-6

"Methods, Processes, and Tools for Collaboration -The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types.---Bryn Williams-Jones, Associate Research Fellow, Pfizer The pharmaceutical industry utilizes an extended network of ..."






Drug Efficacy, Safety, and Biologics Discovery(1st Edition)
Emerging Technologies and Tools (Wiley Series on Technologies for the Pharmaceutical Industry)
by Sean Ekins, Jinghai J. Xu
Hardcover, 424 Pages, Published 2009 by Wiley
ISBN-13: 978-0-470-22555-4, ISBN: 0-470-22555-6

""Drug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools" covers key emerging technologies in pharmaceutical R & D and how they have substantially impacted (or are currently impacting) drug discovery. The cross-disciplinary collaborations implicit in integrating these technologies with drug discovery operations will fuel the engine for future innovations. This book cuts across the multiple areas of drug discovery ..."






Computational Toxicology(1st Edition)
Risk Assessment for Chemicals (Wiley Series on Technologies for the Pharmaceutical Industry)
by Sean Ekins
Hardcover, 432 Pages, Published 2018 by Wiley
ISBN-13: 978-1-119-28256-3, ISBN: 1-119-28256-X

"A key resource for toxicologists across a broad spectrum of fields, this book offers a comprehensive analysis of molecular modelling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals.•    Provides a perspective of what is currently achievable with computational toxicology and a view to future developments•    Helps readers overcome questions of data sources, curation, treatment, and how ..."






Computer Applications in Pharmaceutical Research and Development(1st Edition)
(Wiley Series in Drug Discovery and Development)
by Sean Ekins, Binghe Wang
Hardcover, 844 Pages, Published 2006 by Wiley-Interscience
ISBN-13: 978-0-471-73779-7, ISBN: 0-471-73779-8

"A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, includi ..."






Pathway Analysis for Drug Discovery(1st Edition)
Computational Infrastructure and Applications
by Anton Yuryev, Sean Ekins
Hardcover, 336 Pages, Published 2008 by Wiley
ISBN-13: 978-0-470-10705-8, ISBN: 0-470-10705-7

"This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug ..."






Pharmaceutical and Biomedical Project Management in a Changing Global Environment(1st Edition)
by Scott D. Babler, Sean Ekins
Hardcover, 400 Pages, Published 2010 by Wiley
ISBN-13: 978-0-470-29341-6, ISBN: 0-470-29341-1

"Pharmaceutical and Biomedical Portfolio Management in a Changing Global Environment explores some of the critical forces at work today in the complex endeavour of pharmaceutical and medical product development.  Written by experienced professionals, and including real-world approaches and best practice examples, this new title addresses three key areas – small molecules, large molecules, and medical devices - and provides hard-to-find, ..."






The Agile Approach to Adaptive Research(1st Edition)
Optimizing Efficiency in Clinical Development (Wiley Series on Technologies for the Pharmaceutical Industry)
by Michael J. Rosenberg, Sean Ekins
Hardcover, 304 Pages, Published 2010 by Wiley
ISBN-13: 978-0-470-24751-8, ISBN: 0-470-24751-7

"Apply adaptive research to improve results in drug development The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently. Wi ..."






The Engines of Hippocrates(1st Edition)
From the Dawn of Medicine to Medical and Pharmaceutical Informatics (Wiley Series on Technologies for the Pharmaceutical Industry)
by Barry Robson, O. K. Baek, Sean Ekins
Hardcover, 598 Pages, Published 2009 by Wiley
ISBN-13: 978-0-470-28953-2, ISBN: 0-470-28953-8

"A unique, integrative look at information-based medicine The convergence of medical science, biology, pharmacology, biomedical engineering, healthcare, and information technology is revolutionizing medical and scientific practice, and has broader social implications still being understood. The Engines of Hippocrates provides a unique, integrative, and holistic look at the new paradigm of information-based medicine, covering a bro ..."






Pharmaceutical Applications of Raman Spectroscopy
by Slobodan Sasic, Sean Ekins, Anne E. Magurran
Hardcover, 268 Pages, Published 1994 by Pharmaceutical Applications Of Raman Spectroscopy
ISBN-13: 978-0-8138-1013-3, ISBN: 0-8138-1013-2

"Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharma ..."






Predictive Approaches in Drug Discovery and Development(1st Edition)
Biomarkers and In Vitro / In Vivo Correlations
by Richard Lalonde, J. Andrew Williams, Jeffrey R. Koup, David D. Christ, Sean Ekins, Kasabov N.
Hardcover, 408 Pages, Published 2012 by Wiley
ISBN-13: 978-0-470-17083-0, ISBN: 0-470-17083-2

"Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.  Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics ..."






Pharmaceutical Data Mining(1st Edition)
Approaches and Applications for Drug Discovery (Wiley Series on Technologies for the Pharmaceutical Industry)
by Konstantin V. Balakin, Sean Ekins, Ahmed H.U.
Hardcover, 565 Pages, Published 2009 by Wiley
ISBN-13: 978-0-470-19608-3, ISBN: 0-470-19608-4

"Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, wh ..."






Computational Toxicology
Risk Assessment for Chemicals
by Sean Ekins
432 Pages, Published 2018 by John Wiley & Sons
ISBN-13: 978-1-119-28258-7, ISBN: 1-119-28258-6

"27 Guy, R.H. and Hadgraft, J. (1989). Selection of drug candidates for transdermal drug delivery, in Transdermal Drug Delivery (eds J. Hadgraft and R.H. Guy), Marcel Dekker, New York, pp. ... 29 Karande, P., Jain, A., Ergun, K. et al. (2005) ..."






Collaborative Computational Technologies for Biomedical Research(1st Edition)
by Sean Ekins, Alpheus Bingham, Antony J. Williams
Printed Access Code, 480 Pages, Published 2011 by Wiley-Blackwell
ISBN-13: 978-1-118-02603-8, ISBN: 1-118-02603-9

"Covering a neglected but important topic of management and information technology collaborations in drug discovery and development, this book discusses the state–of–the–art collaborative and computing techniques for the pharmaceutical industry. Tackling problems thoroughly, from both the human collaborative and the data and informatics side, this volume is relevant to the day–to–day activities of running a laboratory or a collaborative ..."






Computational Toxicology(1st Edition)
Risk Assessment for Pharmaceutical and Environmental Chemicals (Wiley Series on Technologies for the Pharmaceutical Industry)
by Sean Ekins
Hardcover, 830 Pages, Published 2007 by Wiley-Interscience
ISBN-13: 978-0-470-04962-4, ISBN: 0-470-04962-6

"A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) mo ..."






Computational Toxicology
Risk Assessment for Chemicals
by Sean Ekins
432 Pages, Published 2018 by John Wiley & Sons
ISBN-13: 978-1-119-28257-0, ISBN: 1-119-28257-8

"Sean Ekins, Series Editor Computational Toxicology: Risk Assessment for Pharmaceutical and Environmental Chemicals Edited by Sean Ekins Pharmaceutical Applications of Raman Spectroscopy Edited by Slobodan Sašić Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications Edited by Anton Yuryev Drug Efficacy, Safety, and Biologics Discovery: Enmerging Technologies and Tools Edited by Sean Ekins and Jinghai J. ..."






The Future of the Pharmaceutical Industry
by Sean Ekins, Bernard Munos
208 Pages, Published 2018 by Academic Press
ISBN-13: 978-0-12-397215-6, ISBN: 0-12-397215-9

"In a provocative look at the pharmaceutical industry, this book breaks through current biases to bring all opinions together and allow readers to form their own vision and strategies for the future."






High Throughput Screening Methods(1st Edition)
Evolution and Refinement (Chemical Biology)
by Joshua A. Bittker, Nathan T. Ross, Claes Andersson, Sean Ekins, Douglas Auld, Mark Wigglesworth, Christopher Hale, Christopher Mader, Kira J. Weissman, Peizin Zhu, Jaime Cheah, Tom Brown, Damien Young, Michael Mesleh, Greg Hoffman, Matthew Robers, Benjamin Haibe-Kains, Richard Eglen, Stephen Hale, Andrea Desouza, Rohan Beckwith, Stuart Schreiber, Soumya Ray
Hardcover, 396 Pages, Published 2016 by Royal Society Of Chemistry
ISBN-13: 978-1-78262-471-4, ISBN: 1-78262-471-6

"High throughput screening remains a key part of early stage drug and tool compound discovery, and methods and technologies have seen many fundamental improvements and innovations over the past 20 years. This comprehensive book provides a historical survey of the field up to the current state-of-the-art. In addition to the specific methods, this book also considers cultural and organizational questions that represent opportunities for fu ..."






Wiley Series on Technologies for the Pharmaceutical Industry Ser.
The Agile Approach to Adaptive Research : Optimizing Efficiency in Clinical Development
by Michael J. Rosenberg, Sean Ekins
288 Pages, Published 2010 by John Wiley & Sons Inc (E)
ISBN-13: 978-0-470-59967-9, ISBN: 0-470-59967-7

"Industry. Sean Ekins, Series Editor Editorial Advisory Board Dr. Renee Arnold ( ACT LLC, USA); Dr. David D. Christ (SNC Partners LLC, USA); Dr. Michael J. Curtis (Rayne Institute, St Thomas' Hospital, UK); Dr. James H. Harwood (Pfizer, USA); Dr. Dale Johnson (Erniliern, USA); Dr. Mark Murcko, (Vertex, USA); Dr. Peter W. Swaan (University of Maryland, USA); Dr. David Wild (Indiana University , USA); Prof. William Welsh (Robert Wood Jo ..."






Wiley Series on Technologies for the Pharmaceutical Industry Ser.
The Engines of Hippocrates : From the Dawn of Medicine to Medical and Pharmaceutical Informatics 5
by Barry Robson, O. K. Baek, Sean Ekins
512 Pages, Published 2009 by John Wiley & Sons
ISBN-13: 978-0-470-46179-2, ISBN: 0-470-46179-9

"Figure 6.2 AGPI for longitudinal integration of health records . Name. Fuzzy search is required because of potential variances, such as Robert A. Smith, Bob Smith, Robert Ashley Smith, Rob Smith, Robert A. Smith Jr., and Robert A Smith III.Also last names of females change upon marriage. . Date of birth. . Gender. . Race. The statutory laws in some countries prohibit collecting this information, although this information is commonl ..."






Virtual Futures for Design, Construction and Procurement
by Peter S. Brandon, Tuba Kocatürk, Sean Ekins
344 Pages, Published 2009 by John Wiley & Sons Inc (E)
ISBN-13: 978-1-4443-0235-6, ISBN: 1-4443-0235-3

"Aish, R. (2004) Extensible computational design tools for exploratory architecture . In: Architecture in the Digital Age: Design and Manufacturing (ed. Branko Kolarvic). New York, Taylor & Francis Group, pp. 243–252. Franken, B. (2004) Take-off-spatial install`ation in Terminal II at Munich Airport. In: Diversifying Digital Architecture (ed. Yu-tung Liu). Basel, Birkh ̈auser, pp. 84–88. Manjubala, I. (2005) Biomimetic mineral–organi ..."



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